Pneumonia and Diarrhea Progress Report 2014

A new report from the International Vaccine Access Center (IVAC) at Johns Hopkins University finds that despite major reductions in pneumonia and diarrhea deaths globally, progress has been slow in the highest-burden countries. The Pneumonia and Diarrhea Progress Report evaluates the progress made by the fifteen highest-burden countries in implementing high-impact interventions from the Global Read More …

New Supplement on Rotavirus Disease Burden in Africa

ROTA Council members Duncan Steele and Umesh Parashar served as two of the guest editors in this month’s The Pediatric Infectious Disease Journal supplement on rotavirus disease burden in Africa. Drs. Parashar and Steele co-authored the introductory article “Preparing for the Scale-up of Rotavirus Vaccine Introduction in Africa: Establishing Surveillance Platforms to Monitor Disease Burden and Read More …

Overcoming Perceptions of Financial Barriers to Rotavirus Vaccine Introduction in Asia

This paper appeared in Human Vaccines & Immunotherapeutics, 2013 Aug 16;9(11). Authors: Nelson EA, de Quadros CA, Santosham M, Parashar UD, Steele D. A two-page summary of the paper can be found here. Abstract Despite a WHO recommendation in 2009, reaffirmed in 2013, that all countries should consider introducing rotavirus vaccines into their National Immunization Read More …

Rotavirus Vaccine Proves Itself ‘On the Ground’

This post first appeared on SciDev.Net.  [LA PAZ] A WHO-recommended vaccine for rotavirus infection has proved effective in Bolivia, the first low-income country to introduce it, researchers have reported. Rotavirus is the leading cause of diarrhoea-related deaths in most of the developing world. The WHO recommends two vaccines for all children worldwide — RV1, which Read More …

Progress on Rotavirus Prevention – Globally and in India – A Conversation with Dr. Mathu Santosham

This post first appeared on the Johns Hopkins Bloomberg School of Public Health International Vaccine Access Center (IVAC) blog. The Integrated Global Action Plan for Pneumonia and Diarrhoea (GAPPD) was launched last month. Now this week we’ve learned that a new rotavirus vaccine from India, Bharat Biotech‘s ROTAVAC, looks promising, and The Lancet featured results from the Read More …

Global Enteric Multicenter Study (GEMS): Rotavirus #1 Cause of Diarrhea in Infants

The Global Enteric Multicenter Study (GEMS), the largest study on diarrheal disease in developing countries to date, confirmed rotavirus is the leading cause of diarrheal diseases among infants. The study involved more than 20,000 children from seven sites across Asia and Africa, and found that approximately one in five children under the age of two Read More …

Study: New Rotavirus Vaccine Developed in India Proves Effective

The Government of India’s Department of Biotechnology and Bharat Biotech announced today the positive results from a Phase III clinical trial of a rotavirus vaccine, ROTAVAC®, developed and manufactured in India. Data from the trial  showed ROTAVAC® significantly reduced severe rotavirus diarrhea by more than half—56 percent during the first year of life, with protection continuing Read More …

Breakthrough in Child Immunisation

Professor Julie Bines has led a team to make a world breakthrough in reducing child mortality, with the development of a natural immunisation which can now be administered at birth. The World Health Organisation recommendation that all children be immunised to prevent severe rotavirus gastroenteritis, a deadly diarrhoeal disease, is more likely to become a reality with Read More …

Survey of national immunization programs and vaccine coverage rates in Asia Pacific countries

Mathuram Santosham co-authored an article that showed protection against pneumococcus, rotavirus, and human papillomavirus infections are highly inadequate in most of the countries in the Asia Pacific region. Promoting coverage of newly developed vaccines will benefit a great number of children in this area. To read the rest of this article, please click here.

Potential intussusception risk versus health benefits from rotavirus vaccination in Latin America

With the recent postlicensure identification of an increased risk of intussusception with rotavirus vaccine, the 14 Latin American countries currently using rotavirus vaccine must now weigh the health benefits versus risks to assess whether to continue vaccination. This research found that the health benefits of vaccination far outweigh the short-term risks and support continued rotavirus Read More …